PARALLEL GOLD ENHANCEMENT OF QUANTUM DOTS 565/655 FOR DOUBLE-LABELLING CORRELATIVE LIGHT AND ELECTRON MICROSCOPY ON HUMAN AUTOPSIED SAMPLES

Parallel gold enhancement of quantum dots 565/655 for double-labelling correlative light and electron microscopy on human autopsied samples

Abstract Cadmium selenide quantum dots (QDs) are fluorescent and electron-dense nanoparticles.When used as reporter of immunolabeling, this dual visibility is essential for direct comparison of its fluorescent signals on light microscopy (LM) and their ultrastructrual counterparts on electron microscopy (EM) as correlative light and electron micros

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Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia

Escape from chemotherapy-induced Douches apoptosis is a hallmark of drug resistance in cancer.The recent identification of alternative programmed cell death pathways opens up for possibilities to circumvent the apoptotic blockade in drug resistant cancer and eliminate malignant cells.Indeed, we have recently shown that programmed necrosis, termed n

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